The esters of erythromycin
نویسندگان
چکیده
منابع مشابه
Assay of erythromycin esters.
To the Editor: It was disturbing to read the article entitled “Studies of the Stability of 18 Chemical Constituents,” in the December, 1972, issue of Clinical Chemistry (1). The authors define their conditions of collection and storage but do not, however, make it clear what their object is. If the objective was to show stability of serum before analysis, then their data are misleading. For exa...
متن کاملAntibacterial activity of 2'-esters of erythromycin.
The effect of esterification at the 2'-position of desosamine on the antibacterial activity of erythromycin was investigated by determining the bacteriostatic and bactericidal activities of erythromycin and a number of its 2'-esters on S. aureus and relating these activities to the hydrolysis rates of the esters. These studies, together with comparison of the inhibition of protein synthesis in ...
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A randomized crossover study in 16 healthy volunteers given multiple doses of erythromycin base enteric-coated tablets or erythromycin estolate capsules revealed essentially no difference in the resultant plasma concentration of bioactive erythromycin. This similarity in bioactivity persisted despite the fact that total eryghromycin levels (bioactive erythromycin base plus bioinactive erythromy...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 1979
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/5.6.633